Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients

Completed

• Conditions: Intervertebral Disc Displacement; Low Back Pain; Intervertebral Disc Degeneration
• Interventions: Radiation: x-ray, MRI

• Registration Number: NCT02351206
• Lead Sponsor: Jaseng Hospital of Korean Medicine

Brief Summary

As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP. The investigators therefore assessed the feasibility of using X-ray disc space height measurements as a predictive evaluation method of lumbar disc herniation (LDH) and degeneration in LBP patients in their early 20s.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2014-10
• Study Completion: 2014-11
• Study First Submitted: 2015-01-27
• Study First Submitted QC: 2015-01-29
• Study First Posted: 2015-01-30
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-05
• Last Update Posted: 2018-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 389

Inclusion Criteria

• Age 20-25 years
• L-spine X-ray and L-spine MRIs taken within a week of the other test
• Native Korean ethnicity

Exclusion Criteria

• Scoliosis with a Cobb's angle of ≥20°
• Significant vertebral deformity of any etiology (e.g. spondylolisthesis, fracture, spondylitis, neoplasm)
• Previous spinal surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
The experimental group	x-ray, MRI	Patients with intervertebral disc protrusion, extrusion, or migration at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.
The control group	x-ray, MRI	Patients with normal or disc bulging readings at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.

Primary Outcome Measures

Name	Time	Method
The distance between the 2 midpoints of the inferior and superior borders of the vertebral bodies surrounding the L4/5 intervertebral disc space divided by the AP diameter of the inferior border of the L4 vertebral body	Baseline