Intra- and Inter-fraction Changes in Radiation Therapy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Changes of volumes from baseline of organs at risk during and after radiation therapy.
研究概览
简要总结
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
详细描述
The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •°Completed radiation therapy
排除标准
- •°Subjects who refuse voluntary participation
结局指标
主要结局
Changes of volumes from baseline of organs at risk during and after radiation therapy.
时间窗: 2 years
Changes of organs at risk volumes (cm\^3) during and after radiation therapy.
次要结局
- Changes of volumes from baseline or tumors during and after radiation therapy.(2 years)
研究者
Eric Paulson
Associate Professor
Medical College of Wisconsin