Protein in Preterm Infant Nutrition (PiPIN)

Completed

• Conditions: Preterm infant < 31 weeks; Reproductive Health and Childbirth - Childbirth and postnatal care

• Registration Number: ACTRN12606000525583
• Lead Sponsor: Associate Professor Maria Makrides, Child Nutrition Research Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-12-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Infants born <31 weeks gestation at Women's & Children's Hospital Adelaide who are receiving breast milk.

Exclusion Criteria

Infants with major congenital or chromosomal abnormalities which are known to affect growth such as major heart defects, cystic fibrosis.Infants where a high protein intake is contraindicated such as Phenylketonuria, disorders of the urea cycle.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
inear growth (increase in recumbent length)[Weekly, & Discharge (D/C) or Estimated Date of Delivery (EDD)]

Secondary Outcome Measures

Name	Time	Method
Weight gain: grams [Daily, D/C or EDD];Head circumference: centimetres[Weekly, D/C or EDD];Body composition: Bioelectrical Impedance Spectroscopy[Fortnightly D/C or EDD ];Serum albumin, Urea, total protein, electrolytes, acid base[Weekly, D/C or EDD];Amino acid profile (blood & urine): tandem mass spectroscopy[Weekly, weekly & D/C or EDD]