Acupoint Stimulation Alleviates Postoperative Nausea and Vomiting

Not Applicable

• Conditions: PONV
• Interventions: Device: transcutaneous electrical acupoint stimulation

• Registration Number: NCT05396716
• Lead Sponsor: Zhihong LU

Brief Summary

Incidence of postoperative nausea and vomiting (PONV) could be high as 60% after liver surgery. Acupoint stimulation has been proved to decrease PONV. In this study, we will investigate the effect of transcutaneous electrical acupoint stimulation on incidence of PONV after liver surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-05
• Study First Submitted: 2022-05-25
• Study First Submitted QC: 2022-05-25
• Last Update Submitted: 2022-05-25
• Study Start: 2022-05-30
• Study First Posted: 2022-05-31
• Last Update Posted: 2022-05-31
• Primary Completion: 2023-05-30
• Study Completion: 2023-05-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 158

Inclusion Criteria

• age ≥18 years
• scheduled for elective liver surgery under general anesthesia

Exclusion Criteria

• body mass index less than 18 kg/m2 or higher than 30 kg/m2
• American Society of Anesthesiologists status higher than Ⅲ
• patients with contraindication to transcutaneous electrical stimulation, including skin damage, infection or implantable electrical device
• suspected or existed abuse of drug or alcohol
• pregnant or breeding women
• history of neurological or psychiatric disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
transcutaneous electrical acupoint stimulation	transcutaneous electrical acupoint stimulation	-

Primary Outcome Measures

Name	Time	Method
incidence of nausea and vomiting by 24 hours after surgery	from end of surgery to 24 hours after surgery, in a total of 24 hours

Secondary Outcome Measures

Name	Time	Method
Quality of recovery score at 24 hours after surgery	from end of surgery to 24 hours after surgery, in a total of 24 hours
score of nausea and vomiting by 48 hours after surgery	from end of surgery to 48 hours after surgery, in a total of 48 hours
score of nausea and vomiting in PACU(post-anesthesia care unit)	from end of surgery to discharge from PACU, in an average of 30 minutes
Quality of recovery score at 48 hours after surgery	from end of surgery to 48 hours after surgery, in a total of 48 hours
incidence of nausea and vomiting in PACU (post-anesthesia care unit)	from end of surgery to discharge from PACU(post-anesthesia care unit), in an average of 30 minutes
incidence of nausea and vomiting by 48 hours after surgery	from end of surgery to 48 hours after surgery, in a total of 48 hours
score of nausea and vomiting by 24 hours after surgery	from end of surgery to 24 hours after surgery, in a total of 24 hours
postoperative in-hospital stay	from end of surgery to discharge from hospital, in an average of 7 days
death by 6 months after surgery	from end of surgery to 6 months after surgery, in a total of 6 months