Acupoint Stimulation Alleviates Postoperative Nausea and Vomiting
Not Applicable
- Conditions
- PONV
- Registration Number
- NCT05396716
- Lead Sponsor
- Zhihong LU
- Brief Summary
Incidence of postoperative nausea and vomiting (PONV) could be high as 60% after liver surgery. Acupoint stimulation has been proved to decrease PONV. In this study, we will investigate the effect of transcutaneous electrical acupoint stimulation on incidence of PONV after liver surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 158
Inclusion Criteria
- age ≥18 years
- scheduled for elective liver surgery under general anesthesia
Exclusion Criteria
- body mass index less than 18 kg/m2 or higher than 30 kg/m2
- American Society of Anesthesiologists status higher than Ⅲ
- patients with contraindication to transcutaneous electrical stimulation, including skin damage, infection or implantable electrical device
- suspected or existed abuse of drug or alcohol
- pregnant or breeding women
- history of neurological or psychiatric disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method incidence of nausea and vomiting by 24 hours after surgery from end of surgery to 24 hours after surgery, in a total of 24 hours
- Secondary Outcome Measures
Name Time Method Quality of recovery score at 24 hours after surgery from end of surgery to 24 hours after surgery, in a total of 24 hours score of nausea and vomiting by 48 hours after surgery from end of surgery to 48 hours after surgery, in a total of 48 hours score of nausea and vomiting in PACU(post-anesthesia care unit) from end of surgery to discharge from PACU, in an average of 30 minutes Quality of recovery score at 48 hours after surgery from end of surgery to 48 hours after surgery, in a total of 48 hours incidence of nausea and vomiting in PACU (post-anesthesia care unit) from end of surgery to discharge from PACU(post-anesthesia care unit), in an average of 30 minutes incidence of nausea and vomiting by 48 hours after surgery from end of surgery to 48 hours after surgery, in a total of 48 hours score of nausea and vomiting by 24 hours after surgery from end of surgery to 24 hours after surgery, in a total of 24 hours postoperative in-hospital stay from end of surgery to discharge from hospital, in an average of 7 days death by 6 months after surgery from end of surgery to 6 months after surgery, in a total of 6 months
Related Research Topics
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What molecular mechanisms underlie transcutaneous electrical acupoint stimulation in reducing postoperative nausea and vomiting after liver surgery?
How does transcutaneous electrical acupoint stimulation compare to standard antiemetic therapies like ondansetron or dexamethasone in preventing PONV?
Are there specific biomarkers that can predict which patients will respond best to transcutaneous electrical acupoint stimulation for postoperative nausea and vomiting?
What are the potential adverse events associated with transcutaneous electrical acupoint stimulation in liver surgery patients and how are they managed?
What combination therapies or alternative interventions are being explored alongside transcutaneous electrical acupoint stimulation for enhanced PONV prevention in liver surgery?