CTRI/2025/07/091629
Not Applicable
3 期
Effectiveness of Platelet-rich Plasma with Strengthening Exercise versus Conventional Physiotherapy in Knee Osteoarthritis Patients.
Dr Ehsanur Rahman1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月4日最近更新:
概览
- 阶段
- 3 期
- 状态
- Not Applicable
- 发起方
- Dr Ehsanur Rahman
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pain By Numeric Pain Rating Scale(NPRS).
概览
简要总结
This randomized controlled trial compares the effectiveness of platelet-rich plasma (PRP) injection combined with strengthening exercise versus conventional physiotherapy in knee osteoarthritis patients aged 40–70 years. The intervention duration is 8 weeks. Pain (primary outcome) will be measured using NPRS, while secondary outcomes include WOMAC, TUG test, 30-second Sit-to-Stand test, and knee range of motion using a goniometer. Follow-up will be conducted at 6 months to evaluate long-term effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •The inclusion criteria considered patients aged 40-70 years with knee osteoarthritis confirmed by a rheumatologist (grades I-III in the Kellgren-Lawrence score) who had pain, morning stiffness of shorter than 30 minutes, or knee crepitus.
排除标准
- •History of malignancy, infection, active wound in the knee, NSAIDs two days prior to injection, steroid knee injection 3 weeks before the procedure, history of severe knee trauma, pregnancy.
结局指标
主要结局
Pain By Numeric Pain Rating Scale(NPRS).
时间窗: 8 weeks intervention, a follow up will be conducted after 6 months.
次要结局
- Physical Function by Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) score.(Range of Motion By Standard Goniometer.)
研究者
Sree Pallob
Jashore University of Science and Technology
研究点 (1)
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