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Difference of Image Enhanced Endoscopic Findings Between Autoimmune and Helicobacter pylori associated Gastritis

Not Applicable
Conditions
Chronic atrophic gastritis
Registration Number
JPRN-UMIN000019392
Lead Sponsor
Osaka Medical Center for Cancer and Cardiovascular Diseases
Brief Summary

Micromucosal pattern of the corpus mucosa in patients with H. pylori associated gastritis is likely to show Groove type that mimic the antral or intestinal mucosa, while that of autoimmune gastritis was Foveola type suggesting different pathogenesis of these diseases.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

1) History of gastrectomy 2) previously received eradication therapy for H. pylori infection 3) Taking anticoagulant medication or nonsteroidal anti-inflammatory drugs (NSAIDs) within 30 days 4) Hemorrhagic diseases 5) Uncontrolled type 1 diabetes mellitus 6) Cirrhosis 7) Renal failure 8) Pregnancy

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Micromucosal structure observed by magnifying NBI images
Secondary Outcome Measures
NameTimeMethod
Extent of atrophic gastritis observed by autofluorescence images, Histology of biopsy specimen
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