Effects of Expiratory Muscle Training on Cough Efficacy in Children and Adolescents With Cystic Fibrosis
- Conditions
- Cystic Fibrosis
- Interventions
- Other: expiratory muscle training
- Registration Number
- NCT03873688
- Lead Sponsor
- Cigdem Emirza
- Brief Summary
Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by recurrent airway infections, affecting many systems including lung, pancreas and sweat glands. Cough is an important defense mechanism for clearing the secretions that increase in respiratory diseases. There have been studies investigating the effect of expiratory muscle training on disease groups such as chronic obstructive pulmonary disease, multiple sclerosis, parkinson's disease, and the elderly and healthy individuals. Studies that evaluating effects of expiratory muscle training in cystic fibrosis are limited in the literature. The aim of this study was to evaluate the effect of cough strength in children and adolescents with CF and the effect of expiratory muscle training program on cough strength, exercise capacity, respiratory muscle strength and quality of life.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 28
- Diagnosed with cystic fibrosis
- 8-18 years
- Clinically stable during last six weeks
- hemoptysis
- low saturation (SpO2<90%)
- acute lower respiratory tract infection
- cardiac problems (heart failure, arrhythmia, cardiomyopathy, etc.)
- cognitive problems
- pneumothorax
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Experimental Group expiratory muscle training Patients in experimental group will perform expiratory muscle training as home programme for at least five days a week, twice a day for 15 minutes at each session during six weeks by Threshold Positive Expiratory Pressure device. The intensity of training will been setted 30% of the maximal expiratory pressure level. Sham Group expiratory muscle training In sham group, patients will perform expiratory muscle training at home for at least five days a week, twice a day for 15 minutes at each session during six weeks by Threshold Positive Expiratory Pressure device that the intensity of training will been setted 5 cm H₂O.
- Primary Outcome Measures
Name Time Method Cough capacity 6 weeks peak expiratory flow meter
- Secondary Outcome Measures
Name Time Method Respiratory muscle strength every two weeks maximal expiratory pressure, maximal inspiratory pressure
Exercise capacity 6 weeks six minute walking test
Trial Locations
- Locations (1)
Istanbul University Cerrahpasa, Cerrahpasa Medical Faculty
🇹🇷Istanbul, Turkey