The effect of chronic nocturnal non-invasive ventilatory support at home after ventilatory support during acute respiratory failure in patients with Chronic Obstructive Pulmonary Disease (COPD). - RESCUE

niversitair Medisch Centrum Groningen0 个研究点目标入组 200 人开始时间: 待定最近更新: 2024年8月26日

适应症

试验速览

暂无简介。

•1) Chronic Obstructive pulmonary disease (COPD), GOLD severity stage 3 and 4.
•2) Minimally 48 hours without ventilatory support after invasive or non invasive ventilatory support during an acute respiratory failure and maximally until discharge.
•3) Persistent hypercapnia (PaCO2 > 6.0 kPa) during daytime at rest without ventilatory support.

•1) Age < 18 or =>80 years
•2) Significant bronchiectasis with recurrent infections
•3) Significant heart failure
•4) Kyphoscoliosis
•5) Neuromuscular disease
•6) Obstructive sleep apnea (Apnea Hypopnea Index: AHI >15 /hr)
•7) Current use of Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP)
•8) Insufficient motivation for chronic ventilatory support;
•9) Social circumstances making chronic ventilatory support impossible;
•10) Other disease factors limiting life expectations

发起方