The utility of the Mind chapter from Murphys Homoeopathic Medical Repertory in arriving at the simillimum for the treatment of polycystic ovarian syndrome: An experimental study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Change in ovarian morphology, assessed by ultrasonography, measured as change in number of follicles and ovarian volume from baseline to the end of the treatment period, following intervention of individualized homoeopathic similimum by utilising the mind chapter from Murphys repertory.
研究概览
简要总结
This study investigates the efficacy of individualized homoeopathic treatment in women with Polycystic Ovarian Syndrome PCOS using Murphy’s Homoeopathic Medical Repertory. It focuses on the role of emotional and psychological factors in the development and progression of PCOS and evaluates the adaptability and adequacy of Murphy’s repertory, particularly the mind chapter, in identifying the homoeopathic simillimum. Women diagnosed with PCOS will receive individualized constitutional remedies based on detailed case taking, repertorization, and emotional profiling. Outcomes will be assessed through symptomatic improvement, menstrual regularity, and ultrasonographic changes using Rotterdam criteria, with periodic follow ups and statistical analysis to compare pre and post treatment data. The study also aims to identify any gaps in Murphy’s repertory in addressing emotionally diverse PCOS cases and to determine the overall effectiveness of homoeopathic simillimum in PCOS management.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •Female patients from 18-35 years who fulfil the Rotterdams criteria for PCOS.
- •Known Cases of PCOS with history of PCOS for at least more than 3 months to rule out spontaneous, natural regression of functional cysts.
- •All patients with positive finding of Polycystic ovaries in ultrasound scan, clinical hyperandrogenism and menstrual irregularities oligo or amenorrhea, will be included in the study.
- •In the beginning of study, each case will be investigated with Abdominopelvic ultrasound scan, FSH, LH, Prolactin & Thyroid profile.
- •A checklist for clinical record will be created to exclude Cushings syndrome, Congenital adrenal hyperplasia, Hyperprolactinemia, Hyperthecosis & Diabetes mellitus.
- •If at all indications of other disease is evident then such cases will not be considered for the study.
- •Patients who are willing to give written informed consent for research participation will be included in the study.
排除标准
- •Patients with masculine tumours of adrenal gland or ovary will be excluded.
- •Patients with Congenital adrenal hyperplasia, Cushing’s syndrome, Hyperprolactinemia, Hyperthecosis are excluded from the study.
- •Patients with Hypothyroidism, Hyperthyroidism, Diabetes mellitus are also excluded.
- •PCOS patients with endometrial cancer, Hypertension & other severe cardiovascular complications are excluded from the study.
- •Patients with other systemic illness are excluded from study.
结局指标
主要结局
Change in ovarian morphology, assessed by ultrasonography, measured as change in number of follicles and ovarian volume from baseline to the end of the treatment period, following intervention of individualized homoeopathic similimum by utilising the mind chapter from Murphys repertory.
时间窗: Follow-up assessment will be conducted periodically throughout the study period. Patients will be seen every 15 days till menses are regularized. Then onwards every monthly follow-up for symptomatic analysis. USG done before treatment & then onwards every 6 months.
次要结局
- The outcome of the study may help us to understand the utility and gaps in representation of rubrics and thus bridge the gap that exist in Murphy’s repertory(Will be assessed throughout the research study period.)
研究者
Arambya Rajashekar Kalluraya
MNR Homoeopathic Medical college