ACTRN12623000501640招募中Unknown
Quality of Life Following Endoscopic Anti-Reflux Mucosal Ablation versus Nissen Fundoplication for Refractory Reflux: a blinded randomised control trial
Te Whatu Ora - Waitemata (North Shore Hospital)0 个研究点目标入组 50 人开始时间: 2023年5月16日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Symptomatic gastro-oesophageal reflux, despite 2 months twice daily of PPI (proton pump inhibitor) use, and attempts to optimise lifestyle measures contributing to reflux events.
- •Confirmation of pathological reflux via 24-hr Oesophageal pH testing; either
- •Acid Exposure Time >6%
- •DeMeester Score >14.7
- •Positive SAP (symptom association probability) (95%) with SI (Symptom index) >70%
- •Los Angeles (LA) Grade C-D oesophagitis
- •High resolution oesophageal manometry performed in all patients to confirm the absence of major oesophageal motility disorders.
- •Consenting to participate in trial: willing to undergo either ARMA or surgical fundoplication
排除标准
- •Hiatus Hernia; Hill Grade IV or sliding hiatus hernia >2cm
- •Contra-indications to surgical fundoplication
- •-Previous major abdominal surgery precluding laparoscopy
- •-Previous gastric surgery
- •Major motility disorder on HR (high resolution) manometry assessment (as defined by Kahrilas et al)
- •-Minor motility disorder with functional impact (abnormal Ba swallow or solid food challenge)
研究者
相似试验
尚未招募
不适用
Quality of life and endoscopic finding according to the reconstruction methods after laparoscopic distal gastrectomy for gastric cancerNeoplasmsKCT0004255The Catholic University of Korea, Seoul St. Mary's Hospital189
进行中（未招募）
Unknown
Postoperative pain and quality of life after Canal Treatment with mechanized instruments: clinical studyPulp degenerationC07.793.237RBR-10kbw6nxCentro Universitário do Maranhão - UNICEUMA
招募中
Unknown
The clinical outcomes after endoscopic mucosal resection or endoscopic submucosal dissection of colorectal neoplasms: A multicenter registryPatients with colorectal neoplasiacolorectal neoplasiacolonoscopyJPRN-jRCT1052230113ouis HS Lau2,500
招募中
不适用
Outcomes for patients undergoing endoscopic therapy for Barrett’s related neoplasia: over 10-year experience from the Dutch Barrett Expert CentersBarrett's esophagusBarrett's related neoplasiaNL-OMON29089ead site:Academic Medical Center Amsterdam (AMC)Collaborating centers:•Sint Antonius Hospital Nieuwegein•Catharina Hospital, Eindhoven•University Medical Center, Utrecht•Isala Clinics, Zwolle•Erasmus Medical Center, Rotterdam•Haga Hospital, Den Haag•University Medical Center, Groningen2,000
Enrolling By Invitation
不适用
Quality of Life Assessment of Chronic Pancreatitis Endoscopic InterventionsChronic PancreatitisNCT03632616University of Colorado, Denver500