A comparative study of two drugs
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/05/067274
- Lead Sponsor
- Dr Ambati Mounika
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Patients of ASA grade 1 and 2 who are undergoing
elective surgery under general anesthesia
2 Patients who consent to participate in the study
3 Patients having informant available
Exclusion Criteria
1Difficult airway
2Hypertension
3Diabetes mellitus
4ischemic heart disease
5renal diseases
6Cerebrovascular Disease
•Patients on beta blockers
alpha blockers
•Bronchial asthma
•Allergy to study drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dexmeditomidine 1µ/Kg given slowly over 10 minutes intravenously 5 minutes prior to induction, attenuates the cardiovascular responses to laryngoscopy and intubation in a better manner than Labetalol 0.25mg/Kg.Timepoint: post intubation vitals are measured every 3minutes for first 15minutes
- Secondary Outcome Measures
Name Time Method To observe the effect of Dexmedetomidine in attenuating the hemodynamic stress response during Laryngoscopy and intubation <br/ ><br>2)To observe the effect of labetalol in attenuating hemodynamic stress response during Laryngoscopy and Intubation <br/ ><br>3)To compare between Dexmedetomidine and Labetalol in the specified dosage. <br/ ><br>Timepoint: post intubation vitals are measured every 3minutes for first 15minutes