NL-OMON50968尚未招募不适用
Effectiveness of methylphenidate in adults with phenylketonuria and attention-deficit/hyperactivity disorder: An N-of-1 series - MPH4PK
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 5
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Minimum age of 18 years.
- •- A definite diagnosis of classical PKU according to well-established
- •guidelines.
- •- Meet DSM-5 criteria for ADHD and diagnosed with ADHD by an expert
- •multidisciplinary team consisting of an ID physician, a psychologist, and a
- •psychiatrist.
- •- Presence of a patient*s caregiver for proxy-reports.
排除标准
- •- Unable to take and/or send in dried blood spots.
- •- Presence of ADHD in first- and second-degree relatives.
- •- Presence of a contra-indication for treatment with methylphenidate (e.g.
- •cardiovascular disease).
- •- Planned surgery and/or general anaesthesia during the trial.
- •- Pregnancy.
- •- Breastfeeding (females).
- •- During treatment with non-selective, irreversible monoamine oxidase (MAO)
- •inhibitors, or within a minimum of one month of discontinuing those drugs.
- •- Current substance or alcohol abuse.
- •- Unable to swallow tablets / capsules.
研究者
相似试验
进行中（未招募）
1 期
Effectiveness of methylphenidate for treating ADHD in adultswith PKPhenylketonuria, ADHDEUCTR2021-001174-29-NLAmsterdam UMC5
尚未招募
不适用
Effectiveness of methylphenidate in adults with phenylketonuria and attention-deficit/hyperactivity disorder: An N-of-1 seriesPhenylketonuriaNL-OMON24320Amsterdam UMC / Amsterdam Public Health (Personalized Medicine)5
已完成
2 期
Investigating the effectiveness of methylphenidate and combination of magnesium and zinc and calcium in treatment of patients with attention deficit hyperactivity disorder (ADHD) in Zahedan CityIRCT2015092624209N1Vice Chancellor for Research and Technology at Zahedan University of Medical Sciences and Health Ser40
已完成
3 期
Investigating the effectiveness of methylphenidate and multi chain polyunsaturated fatty acids in treatment of patients with attention deficit hyperactivity disorder (ADHD) in Zahedan CityAttention deficit hyperactivity disorder (ADHD).Disturbance of activity and attentionIRCT2015092724209N2Vice Chancellor for Research and Technology at Zahedan University of Medical Sciences and Health Ser40
已完成
3 期
Methylphenidate and atomoxetine in attention deficit hyperactivity disorderIRCT20110802007202N15Tehran University of Medical Sciences36