Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Serum free testosterone
研究概览
简要总结
Cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population
详细描述
In this study, we conduct a cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population. Age-matched non-HIV infected MSM group will be used as comparison group. We will also determine the risk factors associated with male hypogonadism (age, duration of HIV infection, comorbidities, BMI, ART use). Correlation will be made between serum testosterone levels and sexual function, vitality, exercise capacity, mood, and bone mineral density.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •HIV-infected men who have sex with men
- •HIV non-infected men
排除标准
- •Use of testosterone supplement, anabolic steroid in the past one year.
- •History of pituitary , adrenal or gonad diseases
- •History of pituitary surgery or radiation therapy
- •History of systemic chemotherapy
- •Active opportunistic infection under treatment
- •Severe hepatic, renal or cardiac impairment
结局指标
主要结局
Serum free testosterone
时间窗: 2021-2030
We use serum free testosterone to study the prevalence of hypogonadism in HIV-infected MSM population
Symptoms of androgen deficiency
时间窗: 2021-2030
We use the score of Androgen Deficiency in Aging Males (ADAM) questionnaire to study the prevalence of hypogonadism in HIV-infected MSM population
次要结局
未报告次要终点