Prevention of oral cancer by tea: a mechanism study

Georgetown University (USA)0 个研究点目标入组 64 人开始时间: 2012年1月6日最近更新: 2016年10月17日

适应症

试验速览

暂无简介。

•1. Must be aged 18 to 60 years
•2. Potential subjects should have been smoking for at least two years and be currently smoking at least 1/2 pack (10 cigarettes) per day
•3. Subjects should be, in general, on a low flavonoid diet (low plant-based diet)

•1. Allergic to tea or caffeine
•2. Have oral leukoplakia or evidence of oral lesions
•3. Regularly take medications containing caffeine, principally analgesics and 'cold' medicines (American Drug Index 1999)
•4. Habitually drink more than two cups of coffee, tea, or caffeinated sodas per day
•5. Habitually drink energy drinks (such as Red Bull, Jolt, Monster, etc.) each day
•6. Drink more than two servings in one day of: 40% proof alcoholic beverages (3 oz), beer (12 oz), wine (6 oz), or any cocktail
•7. Suffering from cancer
•8. Have been treated with chemotherapy or radiotherapy within the past five years
•9. Have cardiac arrhythmias or other heart disease or have been advised not to take excessive caffeine
•10. Strict vegetarians
•11. Taking alternative medications that have primarily an antioxidant effect (American Drug Index 1999)
•12. Taking Vitamin A, C and E in doses > 1-1/2 x the RDA
•13. Have serum levels of Vitamin A, serum carotenoids or alpha-tocopherol above the upper limits of normal
•14. Have high blood pressure

发起方

Georgetown University (USA)