To study the effect of different doses of butarphanol injected in the outermost space around the spinal cord for postoperative pain relief in patients undergoing casearean sectio
- Conditions
- Health Condition 1: null- 100 pregnant patientsASA grade I or IIage group of 18-40 years (complete years), undergoing elective caesarean section using combined spinal-epidural anaesthesia technique
- Registration Number
- CTRI/2017/10/010165
- Lead Sponsor
- Deen Dayal Upadhyay Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
A total of 100 parturients belonging to ASA grade I or II in the age group of 18-40 years (complete years), undergoing elective caesarean section using combined spinal-epidural anaesthesia technique were included in the study.
1. Parturients having respiratory, cardiovascular or neuromuscular disease.
2. Parturients with complicated pregnancy or foetal distress.
3. Spinal anomaly or history of back surgery.
4. Patients recieving drugs that modify pain perception like NSAIDS, steroids,
psychotropic, hypnotic drugs and anticoagulants.
5. Known hypersensensitivity to any of the study drug.
6. History of atopy or pruritis.
7. History of obstructive sleep apnoea.
8. Patients with bleeding disorder or any other comorbidity where spinal or epidural anaesthesia would otherwise be a relative contraindication were excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare the efficacy of different doses of epidural butorphanol (0mg, 0.5mg, 1mg, 2mg) with 0.125% bupivacaine (9ml) combination for postoperative analgesia following caesarean section using combined spinal-epidural anaesthesia techniqueTimepoint: 24 hours
- Secondary Outcome Measures
Name Time Method To study and compare the side effects, if observed with any of the study drug combinations used.Timepoint: 24 hours