The Eye in Orbit: UCF Adaption
- Conditions
- Spaceflight Associated Neuro-Ocular SyndromeSANS
- Registration Number
- NCT06092359
- Lead Sponsor
- University of Central Florida
- Brief Summary
The goal of this study is to understand the impact of space travel on the eyes. Space flight impacts numerous aspects of ocular anatomy and physiology. Current hypotheses are based on pressure changes within and around the optic nerve. Retinal and choroid blood drainage may be affected by microgravity associated cerebrospinal fluid pressure changes. Recently, a new imaging modality, Optical Coherence Tomography Angiography (OCTA), has been able to reveal micro vascular changes in the retina and choroid. To date, no microgravity ocular imaging tests have been published using OCTA. In this study the researchers aim to describe microgravity circadian choroidal and retinal vasculature using multimodal imaging including OCTA to better understand space associated ocular changes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1
- astronauts in the AX1/Rakia mission, which was scheduled for space flight in late March 2022.
- adults unable to consent
- individuals who are not yet adults (infants, children, teenagers) -
- pregnant women
- prisoners.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Asses early changes in ocular physiology as risk factor for Spaceflight Associated Neuro-Ocular Syndrome (SANS). 4 months To examine early changes in ocular physiology following exposure to microgravity and asses these changes as risk factor for Spaceflight Associated Neuro-Ocular Syndrome (SANS). 4 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Central Florida
🇺🇸Orlando, Florida, United States