A Randomized Controlled Trial Comparing Intraperitoneal Low Molecular Weight Heparin and Unfractionated Heparin in Peritoneal Dialysis Related Peritonitis

Phase 3

Completed

• Conditions: peritoneal dialysis peritonitis; Intraperitoneal enoxaparin, Ultrafiltration (UF), Peritoneal solute transport rate (PSTR)

• Registration Number: TCTR20220318003
• Lead Sponsor: o

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-01-12
• Study Start: 2022-03-18
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

1. Age more than 18 years
2. PD patient with peritonitis

Exclusion Criteria

1. Previous peritonitis within 1 month
2. History of recent bleeding in 1 month
3. current use of low molecular weight anticoagulants, 4. drug allergy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ltrafiltration At day 7, 14, 30, 60 Milliliter

Secondary Outcome Measures

Name	Time	Method
To compare peritoneal solute transfer rate(PSTR) before and after intervention Complete antibiotics treatment PET,To compare technical failure at 1 month and 2 months after treatment Day 14, 30, 60 (Technical failure defined as shift mode, death or remove catheter ),To compare the changes of interleukin-6 in dialysis fluids and blood before and after treatment Before and after Complete antibiotics treatment Pg per dl,Adverse effect Day 14, 30, 60 Gi bleeding, death