Evaluation of Organized Human Papilloma Virus (HPV) Screening of 23-29-year-old Women
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 180,000
- 试验地点
- 4
- 主要终点
- Incidence of cervical cancer
研究概览
简要总结
The aim of the trial is to determine whether organized screening with primary HPV analysis provide higher cancer protection in the age group 23-29 years compared to primary cytology.
详细描述
The aim is to investigate whether primary HPV analysis in the organized cell sampling program for women in the age group 23-29 provides higher cancer protection compared to the current method where cell samples are primarily analyzed with cytology. In this study, all women in the age group 23-29 in the Stockholm and Skåne Region of Sweden will participate. Age is defined by year of birth. For 2020, women born 1991-1997 are included. Sampling and collection of samples is the same as for cytology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 23 Years 至 29 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women ages 23-29 invited to screening.
排除标准
- •Women who do not show up for screening or do not consent.
结局指标
主要结局
Incidence of cervical cancer
时间窗: Measured once during 1 year, year 10.
Cervical cancer incidence in the intervention group compared to a historical control group.
次要结局
- Cost-effectiveness of the new screening method(Measured once during 1 year, year 10.)
研究者
Joakim Dillner
Professor of Infectious Disease Epidemiology; Director of R&D
Karolinska Institutet