Lifestyle Interventions to Reduce Diabetes Risk

Not Applicable

Completed

• Conditions: Glucose Intolerance; Diabetes Mellitus, Type 2

• Registration Number: NCT00006162
• Lead Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Brief Summary

Type 2 diabetes is more frequent in Japanese Americans than in Japan or the U.S. non-Hispanic white population. This appears to be due to the effects of ''westernization'' to bring out metabolic changes that lead to diabetes. This study will look at whether increased physical activity and dietary changes will reduce or prevent the metabolic changes that lead to type 2 diabetes in Japanese Americans who have impaired glucose tolerance, a condition intermediate between normal glucose tolerance and diabetes.

Detailed Description

Not available

Study Timeline

• Study Start: 1994-10
• Study Completion: 1999-04
• Study First Submitted: 2000-08-08
• Study First Submitted QC: 2000-08-08
• Study First Posted: 2000-08-09
• Status Verified: 2010-03
• Last Update Submitted: 2010-03-01
• Last Update Posted: 2010-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Japanese American
• Confirmed impaired glucose tolerance
• Able to fill out questionnaires

Exclusion Criteria

• Significant exercise-restricting disease
• Poorly controlled hypertension
• Psychiatric disease or dementia
• Already on unusually restrictive diet
• Use of hypolipidemic drugs
• Use of tobacco
• Abnormal blood screening tests
• ECG evidence of ischemic heart disease at rest
• Abnormal maximal Bruce treadmill test

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University of Washington; 🇺🇸 Seattle, Washington, United States