MedPath

Cornea Ectasia Excimer Laser Treatment

Completed
Conditions
Corneal Ectasia
Registration Number
NCT04405882
Lead Sponsor
Bambino Gesù Hospital and Research Institute
Brief Summary

To evaluate efficacy, safety, objective and subjective quality of vision after treatment of cornea ectasia with transepithelial topographic guided laser simultaneous Central Corneal Remodeling (CCR) and Cross-linking (CXL).

Detailed Description

Background To evaluate efficacy, safety, objective and subjective quality of vision after treatment of cornea ectasia performed with transepithelial topographic guided laser simultaneous Central Corneal Remodeling (CCR) and Cross-linking (CXL).

Methods In this retrospective study 8 eyes of 8 patients (mean age 31.50±14.73 years) affected by cornea ectasia underwent simultaneous CCR and CXL. Preoperative and 6 month postoperative uncorrected distance visual acuity (UDVC) and distance corrected visual acuity (DCVA) were measured using the Efficacy and Safety index. Objective and subjective quality of vision were evaluated preoperatively and 6 months postoperatively using corneal morphological irregularity index (CMI), National Eye Institute Visual Function NEI-VFQ25 and NEI-VFQ39 questionnaires.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
8
Inclusion Criteria
  • keratoconus with moderate severity (Amsler-Krumeich stage I-II)
Exclusion Criteria
  • concomitant ocular disease
  • concomitant systemic disease
  • corneal opacities

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
quality of vision6 months postoperatively

corneal morphological irregularity index (CMI)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Luca buzzonetti

🇮🇹

Roma, RM, Italy

© Copyright 2025. All Rights Reserved by MedPath