NCT05134753Unknown3 期
Platelet Rich Fibrin Versus Advanced Platelet Rich Fibrin as Bone Graft Material in Sinus Augmentation (Randomized Controlled Clinical Trial)
适应症
干预措施
试验速览
- 阶段
- 3 期
- 入组人数
- 32
- 主要终点
- Bone quality
研究概览
简要总结
In the present study the main hypothesis , Advanced PRF will improve the bone quality and quantity in sinus augmentation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The Patients with missing posterior maxillary teeth with insufficient available bone for implant placement indicating the need for maxillary sinus floor augmentation before implantation.
- •The Patients should be free from any systemic disease that may affect normal healing of bone, and predictable outcome.
- •The Patients should be free from any sinus disease that might affect the health and integrity of the sinus lining.
- •Assign an informed consent to be involved in the study.
排除标准
- •Patients with any systemic disease that may affect normal healing.
- •Patients with any sinus disease.
研究组 & 干预措施
Study arm
Experimental
Patients will undergo sinus augmentation with advanced PRF
干预措施: Advanced PRF (Biological)
Controlled arm
Placebo Comparator
Patients will undergo sinus augmentation with PRF
干预措施: Control (Biological)
结局指标
主要结局
Bone quality
时间窗: Six months
Histological analysis for core biopsies Available bone quality will be evaluated by measuring the Total Bone Volume (TBV)
次要结局
- Bone quantity(Six months)
研究者
Mahinour magdy mohamed
Resident oral surgery
Cairo University