NCT04400500已完成不适用
Approaches to Differential Diagnosis and Risk Stratification in Patients Hospitalized With Suspected Acute Coronary Syndrome Without Persistent ST-segment Elevation
National Research Center for Preventive Medicine1 个研究点 分布在 1 个国家目标入组 140 人开始时间: 2020年3月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- Clinical outcomes
研究概览
简要总结
To evaluate possibilities of rapid differential diagnosis and risk stratification in patients urgently admitted to the CCU with a suspected acute coronary syndrome without persistent ST-segment elevation (NSTEACS).
详细描述
Single centre prospective non-randomised non-comparative study of patients delivered by ambulance and admitted to the CCU with suspected NSTEACS.
Aims of this study are:
- To characterize the contingent of patients admitted to the CCU with suspected NSTEACS.
- To evaluate possibilities of fast differential diagnosis and risk stratification in patients admitted to the CCU with suspected NSTEACS using clinical data, ECG, biomarker levels (hsTn, NT-proBNP, hsCPR, cardiac FABP) as well as HEART, ADAPT, EDACS, T-MACS, GRACE, ACTION and TIMI scores.
- To evaluate the correlation between clinical data, ECG, biomarker levels (hsTn, NT-proBNP, hsCPR, cardiac FABP) as well as HEART, ADAPT, EDACS, T-MACS, GRACE, ACTION and TIMI scores with presence and severity of coronary atherosclerosis in patients admitted to the CCU (intensive care unit) with suspected NSTEACS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Delivered by ambulance to the CCU with suspected diagnosis "acute coronary syndrome (ACS)".
- •Signed informed consent.
排除标准
- •ACS with persistent ST-segment elevation.
- •Moribund; extremely severe condition on admission with a potentially unfavourable prognosis (cardiogenic shock, coma, cardiac arrest, an urgent need for mechanical ventilation).
- •Overt non-cardiac cause of clinical manifestations at the time of admission (bleeding, pulmonary embolism, aortic dissection, stroke).
结局指标
主要结局
Clinical outcomes
时间窗: 6 monts
Composite of death, (re) infarction, stroke or re-hospitalization
Final diagnosis
时间窗: Up to 1 monts
Final diagnosis - the main reason for urgent hospitalization - according to hospital case history
次要结局
- Death(6 months.)
- (re) infarction(Up to 1 monts)
- Stroke(6 months.)
- Re-hospitalization(6 months.)
研究者
研究点 (1)
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