Dexmedetomidine versus Midazolam for sedation in mechanically ventilated children in Pediatric intensive care unit: A randomized double blind controlled trial.

AIIMS Raipur0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

研究概览

暂无简介。

•Children aged < 12 years admitted in PICU for mechanical ventilation with anticipation to
•require sedation for >24 hours.

•Children with unstable hemodynamics at the time of enrollment (Mean arterial blood pressure < 5th percentile for age, sex, length/height with >2 vasoactive therapy support and/or
•requiring on going resuscitation)
•Children requiring mechanical ventilation for neuromuscular diseases
•Children severe central nervous system pathology like raised intracranial pressure
•irrespective of causes like cerebrovascular accident, status epilepticus.
•Children with developmental delay
•Children with evidence of myocardial dysfunction (ejection fraction < 30%) and bradycardia (HR <60/min)
•Requiring dialysis irrespective of type at the time of enrollment.
•Received general anesthesia 24 hours prior to or planned after the start of study drug infusion
•Children with severe liver pathology like acute liver failure, hepatic encephalopathy,chronic liver disease etc.
•Children with trauma and burns as an admitting diagnosis
•Children ring neuromuscular blockade infusion other than for intubation

发起方

AIIMS Raipur