Does increasing sodium concentration impact plasma sodium and volume with ad libitum drinking in healthy, trained males?

Not Applicable

• Conditions: hyponatraemia; Diet and Nutrition - Other diet and nutrition disorders; Metabolic and Endocrine - Other metabolic disorders

• Registration Number: ACTRN12621000750886
• Lead Sponsor: School of Physical Education, Sport & Exercise Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-15
• Last Update Posted: 21 June 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 11

Inclusion Criteria

Healthy males, Maximal oxygen consumption (VO2max) > 50 ml/kg/min

Exclusion Criteria

Fail to pass a questionnaire to assess readiness to participate in physical activity Physical Activity Readiness Questionnaire (PAR-Q); any chronic diseases (e.g. diabetes, heart problems, high blood pressure, etc.) or be on any prescription medications (except for nutritional supplements).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in plasma sodium concentration [Plasma sodium will be measured at baseline and every 30 min throughout exercise and upon completion of exercise at 3 h (or exhaustion),<br> Outcome will be analysed two ways, 1) as difference from baseline to end (3h or exhaustion), and 2) as change over time across the exercise duration including all measurements: at baseline, every 30 min, and upon completion of 3 h exercise or exhaustion..]

Secondary Outcome Measures

Name	Time	Method
Change in plasma volume as calculated from haemoglobin and haematocrit according to Dill & Costill, 1974.[Haematocrit and haemoglobin will be measured at baseline and every 30 min throughout exercise and upon completion of exercise at 3 h (or exhaustion). Plasma volume change from baseline will be calculated for every 30 min throughout exercise and upon completion of exercise at 3 h (or exhaustion),<br> Outcome will be analysed two ways, 1) as difference from baseline to end (3h or exhaustion), and 2) as change over time across the exercise duration including all measurements: at baseline, every 30 min, and upon completion of 3 h exercise or exhaustion..]