Pakistan Flocculent Health Outcome Study

Not Applicable

Completed

• Conditions: Diarrhea
• Interventions: Other: handwashing; Other: water treatment with sodium hypochlorite; Other: flocculent-disinfectant for water treatment

• Registration Number: NCT01538953
• Lead Sponsor: Centers for Disease Control and Prevention

Brief Summary

This study is designed to evaluate the effect of different methods of drinking water treatment on the occurrence of diarrhea among children living in squatter settlements in Karachi, Pakistan, and the marginal benefit of adding handwashing to water treatment. 260 households will receive a new product which combines flocculation with chlorination to produce clearer, less chemically contaminated drinking water. 260 households will receive dilute sodium hypochlorite, i.e. bleach to treat their water. 260 households will receive soap and encouraged to wash their hands regularly. 260 households will receive both soap and the combination flocculation/chlorination water treatment. 260 households will continue their standard water treatment and handwashing practices. The households will be visited each week for 9 months, and the episodes of diarrhea from each child in the household recorded. The rate of diarrhea between the groups will be compared. At the end of 9 months, households who were part of the standard habits and practice group will receive a water storage vessel and disinfectant.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-03
• Primary Completion: 2003-12
• Study Completion: 2004-01
• Status Verified: 2012-02
• Study First Submitted: 2012-02-21
• Study First Submitted QC: 2012-02-24
• Last Update Submitted: 2012-02-24
• Study First Posted: 2012-02-27
• Last Update Posted: 2012-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8949

Inclusion Criteria

• households in study neighborhoods
• contain a child < 5 years old
• have access to water for handwashing

Exclusion Criteria

• participated in handwashing or drinking water treatment programs with HOPE previously

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Handwashing	handwashing	participants received weekly, in-home handwashing promotion and soap as needed
Water treatment with sodium hypochlorite	water treatment with sodium hypochlorite	-
handwashing and water treatment	handwashing	-
handwashing and water treatment	flocculent-disinfectant for water treatment	-
Water treatment with flocculent-disinfectant	flocculent-disinfectant for water treatment	participants received a supply of flocculent-disinfectant product and instruction to use it to treat drinking water

Primary Outcome Measures

Name	Time	Method
diarrhea longitudinal prevalence

Trial Locations

Locations (1)

Health-Oriented Preventive Education; 🇵🇰 Karachi, Pakistan