Habitual physical activity and exercise capacity in pulmonary hypertensio

Not Applicable

Completed

• Conditions: Pulmonary hypertension; Circulatory System

• Registration Number: ISRCTN14072554
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-03-30
• Study Completion: 2017-02-28
• Last Update Posted: 7 June 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. Patients’ aged greater than 18 years
2. Underlying diagnosis of pulmonary hypertension confirmed by the National Pulmonary Hypertension Service(Newcastle)
3. World Health Organization (WHO) functional Class II to IV

Exclusion Criteria

1. Patients who are unable to provide informed consent
2. Patients with recent syncope
3. Patients with known skeletal and muscle abnormalities
4. Patients with ischaemic heart disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> The change in peak oxygen consumption (VO2) with PH specific treatment.<br><br> Measured at baseline, 3 and 6 months<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Change in habitual physical activity levels with treatment.<br> 2. Change in cardiac output and peripheral muscle oxygen extraction during exercise with PH-specific treatment.<br><br> Measured at baseline, 3 and 6 months<br>