Mucogain Matrix Versus Connective Tissue Graft: "MUCOGREFFE Project"
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 8
- 试验地点
- 2
- 主要终点
- Mean root coverage obtained with both techniques
研究概览
简要总结
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft. We want to show if mucogain matrix used in tunnel technique to recover RTI Cairo recessions defects could be an alternative to connective tissue graft
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with 3 contiguous, symmetrical and bilateral RTI Cairo gingival recessions (Miller Class 1) (i.e. 6 recessions)
- •Patient non-smoker
- •Patient affiliated to social security
- •Patient signed informed consent.
排除标准
- •Patient with or having presented an acute or chronic severe cardiovascular, kidney, liver, gastrointestinal, allergic, endocrine, neuropsychiatric pathology, developed cancer of the upper aero digestive tract treated with radiotherapy
- •Patient with severe hemorrhinopathy
- •Patient treated with oral retinoids, bisphosphonates, oral or anticonvulsants
- •Patient who has taken steroidal or non-steroidal anti-inflammatory therapy, anti-cancer or immunosuppressive chemotherapy within the last 6 months.
- •Patient with contraindication to necessary and pre-, per- or post-operative treatments
- •Follow-up of the patient seemed difficult by the investigator
- •Patient with insufficient oral hygiene incompatible with oral surgery
研究组 & 干预措施
A - Mucogain matrix on right
The patient will receive mucogain matrix on right side and connective tissue graft on left side.
干预措施: Treatment of gingival recessions (Procedure)
B - Mucogain matrix on left
The patient will receive mucogain matrix on left side and connective tissue graft on right side.
干预措施: Treatment of gingival recessions (Procedure)
结局指标
主要结局
Mean root coverage obtained with both techniques
时间窗: 6 months
To compare the mean root coverage obtained with the Creos® Mucogain matrix and connective tissue graft in the treatment of Cairo RT1 class maxillary recessions (Miller Class 1).
次要结局
- Postoperative complications with both techniques(10 days)
- Postoperative pain with both techniques(6 months)