Validation of a Questionnaire to Assess Bronchial Mucus Hypersecretion in Asthmatic Patients. Questionnaire "T-sec" (Secretion Test).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Asthma
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- A questionnaire for bronchial mucus hypersecretion
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
To design and validate a questionnaire that allows objective assessment of the level of bronchial mucus hypersecretion.
Detailed Description
Asthma is a chronic inflammatory disease associated with bronchial mucus hypersecretion (MBH) due to various mechanisms, such as increased mucin secretion, plasma exudation and cytokines. It is currently known that MBH in asthmatic patients is associated with increased mortality and reduced pulmonary function, but there is no tool for its objective assessment. The aim of the study is to design and validate a questionnaire to objectively assess the level of bronchial mucus hypersecretion in patients with asthma.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Aged between 30 and 99 years
- •Clinical diagnosis of asthma
Exclusion Criteria
- •Non-Spanish-speaking patients
- •Inability to complete the questionnaires
- •Failure to sign the informed consent form.
Outcomes
Primary Outcomes
A questionnaire for bronchial mucus hypersecretion
Time Frame: 1 year
To design and validate a questionnaire to objectively assess the level of bronchial mucus hypersecretion
Secondary Outcomes
- Correlation of the results of the questionnaire with exacerbations(1 year)
- Correlation of the results of the questionnaire with ACT(1 year)
- Correlation of the results of the questionnaire with FEV1(1 year)