NCT00497744已完成不适用
Research Study on the Pharmacokinetic Profile of Intraperitoneal Cefepime in Patients With Continuous Ambulatory Peritoneal Dialysis (CAPD) Peritonitis
Hospital Authority, Hong Kong2 个研究点 分布在 1 个国家目标入组 6 人开始时间: 2005年11月最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 6
- 试验地点
- 2
研究概览
简要总结
Cefepime is a broad-spectrum antibiotic used in treating CAPD peritonitis. However, medical knowledge has been lacking with regard to its pharmacokinetic profile after it has been administered intraperitoneally. The current study aims at determining the drug level at different time after the drug has been added into the peritoneal fluid in patients with CAPD peritonitis. The results of this study will finally leads to rational prescription of this drug at correct dosages.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >= 18 years & has been put on CAPD for >= 4 weeks before entering into the study
排除标准
- •Known hypersensitivity to cefepime or other cephalosporin; CAPD peritonitis <= 28 days before being enrolled into the study
- •Antibiotic treatment within 1 week prior to entry into the study
- •Severe exit site or tunnel infection on the day of presentation
- •Any conditions that prompt early removal of Tenckhoff catheter irrespective of clinical response to antibiotic treatment
- •Abdominal malignancy; Any surgical causes of peritonitis
- •Suspected or known fungal or tuberculous peritonitis
- •History of dementia or known mental incompetency
研究者
研究点 (2)
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