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The ACTonHEART Study: Design of a Randomized Controlled Clinical Trial of Acceptance and Commitment Therapy for Cardiac Patients

Not Applicable
Completed
Conditions
Cardiovascular Diseases
Interventions
Behavioral: ACT-based intervention
Behavioral: usual care
Registration Number
NCT01909102
Lead Sponsor
Istituto Auxologico Italiano
Brief Summary

The study will determine whether a brief intervention program based on Acceptance and Commitment Therapy can be effective for the reduction of modifiable risk factors and improvement of psychological well-being in patients referred to cardiac rehabilitation

Detailed Description

The Acceptance and Commitment Therapy is a mindfulness-based intervention which efficacy has been proven in the treatment of depression and anxiety, in stress reduction and in the modification of health- related behaviors in patients with several physical conditions. The application of an acceptance-based program in cardiac patients has revealed high treatment satisfaction and initial evidences of effectiveness in increasing heart-healthy behaviour.

The purpose of the trial is to evaluate the efficacy of a brief group-administered program based on Acceptance and Commitment Therapy in improving patients' ability to address modifiable multiple cardiovascular risk factors and overall psychological well-being, compared with the usual care.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
92
Inclusion Criteria
  • having a current diagnosis of ischemic heart disease (IHD)
  • being affected by major modifiable cardiovascular risk factors that will be assessed through the INTERHEART Modifiable Risk Score.

Only subjects with a full score >9 will be included in the study.

  • between the ages of 18 and 70 years
  • fluency in spoken and written Italian language
  • expression of written informed consent.
Exclusion Criteria
  • cognitive impairment
  • severe psychiatric disorders according to Diagnostic and Statistical Manual-IV TR criteria (APA, 2000).

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ACT-based interventionACT-based interventionThe ACT-based intervention integrates educational topics on heart healthy behaviours with mindfulness and acceptance training regarding difficult thoughts and feelings, clarification of health-related values and commitment to behave in the valued direction while contacting difficult experiences.
Usual careusual careUsual care is based on current guidelines for the long-term multi-disciplinary rehabilitation and prevention of cardiac patients.
ACT-based interventionusual careThe ACT-based intervention integrates educational topics on heart healthy behaviours with mindfulness and acceptance training regarding difficult thoughts and feelings, clarification of health-related values and commitment to behave in the valued direction while contacting difficult experiences.
Primary Outcome Measures
NameTimeMethod
Low-density lipoprotein (LDL)cholesterolBaseline and 12 months

Change from baseline LDL cholesterol level

Blood pressurebaseline and 12 months

Change from baseline resting blood pressure (the mean of 2 measures taken 2 minutes apart with a manual sphygmomanometer)

Body Mass Indexbaseline and 12 months

Change from baseline Body Mass Index. It is calculated as weight in kilograms divided by height in meters squared

Psychological Well-BeingBaseline and 12 months

Change from baseline Psychological Well-Being. It will be measured by the Psychological General Well-Being Inventory. The PGWBI is a self-administered questionnaire composed by six sub-scales: anxiety, depression, positive well-being, self-control, general health and vitality. Higher scores indicate better health.

Secondary Outcome Measures
NameTimeMethod
Physical activityBaseline anf 12 months

Change from baseline physical activity. It will be measured by The International Physical Activity Questionnaire (IPAQ), a self-report questionnaire that assesses the number of days per week and the number of times per day an individual spends doing specific activities.

Smoking cessationAt 1-year follow-up

Self-report of smoking status

Adherence to medicationBaseline and 12 months

Change from baseline adherence to medication. The Modified Morisky Scale will be used. It is a eight-item self-reported measure of medication taking.

Exercise capabilityBaseline and 12 months

Change from baseline exercise capability. The exercise capability will be considered as the maximal power (in Watts) reached during an incremental bicycle stress test.

Health-related quality of lifeBaseline and 12 months

Change from baseline Health-related quality of life. The Short Form-36 questionnaire for evaluation of Quality Of Life is widely used and gives valuable information on Quality Of Life related to health. The patients' Quality Of Life will be assessed through the following eight fractions: physical function, physical role, general health, social function, experience of pain, mental health, emotional role and vitality.

Dietary habitsBaseline and 12 months

Change from baseline dietary habits. They will be assessed through the Mediterranean diet score, a large-scale diet score based on the inherent characteristics of Mediterranean dietary pattern. Questions focused on the frequency of usual consumption of 11 main components of the Mediterranean diet (nonrefined cereals, fruits, vegetables, potatoes, legumes, olive oil, fish, red meat, poultry, full fat dairy products and alcohol).

Trial Locations

Locations (1)

San Luca Hospital, Istituto Auxologico Italiano

🇮🇹

Milano, Italy

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