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A Cross-sectional Study of Congenital Cytomegalovirus Infection in Newborns in China

Completed
Conditions
Congenital Cytomegalovirus Infection
Registration Number
NCT02710864
Lead Sponsor
Jun Zhang
Brief Summary

The primary objectives of this study were to evaluate the incidence of congenital CMV infection in neonates, and assess the concordance of detecting congenital cytomegalovirus (CMV) infection in neonatal saliva and urine samples.

Detailed Description

This Cross-sectional study was conducted to recruit neonates less than 14 days old delivered in Maternal and Child Health Hospitals (MCHHs) of Xinmi City, Jiaxian County, Zhongmu County and Huli District Xiamen City, in China, from June 2015 to June 2016. The aim of this study is to enroll \~1800 neonates, and collect their saliva and urine samples which will be tested the CMV DNA by using real-time PCR.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1510
Inclusion Criteria
  • Neonates aged 0 to 14 days
  • Neonates delivered in MCHHs of Xinmi City, Jiaxian County, Zhongmu County and Huli District Xiamen City
Exclusion Criteria
  • the parents of neonates not comply with our study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of cCMV infection in newbornsup to 5 months
Secondary Outcome Measures
NameTimeMethod
the Kappa value of CMV prevalence between saliva and urine samplesup to 5 months

Trial Locations

Locations (4)

Maternity and Child care of Huli District

🇨🇳

Xiamen, Fujian, China

Maternity and Child care of Zhongmu County

🇨🇳

Zhengzhou, Henan, China

Maternity and Child care of Jiaxian County

🇨🇳

Pingdingshan, Henan, China

Maternity and Child care of Xinmi City

🇨🇳

Zhengzhou, Henan, China

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