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临床试验/CTRI/2025/07/090602
CTRI/2025/07/090602尚未招募2/3 期

Comparative evaluation of intracanal medicaments for effective eradication of Enterococcus Faecalis, a persistent challenge- an in vivo study

Siddhpur Dental College and Hospital1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2025年7月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
120
试验地点
1
主要终点
Reduction in Enterococcus Feacalis count after placement of intracanal medicaments

研究概览

简要总结

Comparative evaluation of intracanal medicaments for effective eradication of Enterococcus Faecalis a persistent challenge an in vivo study

Aim

Comparative evaluation of intracanal medicaments for effective eradication of Enterococcus Faecalis an in vivo study

Objectives

Pre evaluation of E. faecalis count from the root canal after access opening and immediately after instruments

Post evaluation of E.faecalis counts obtained after 7 days placement of triple antibiotic paste

Post evaluation of E.faecalis counts obtained after 7 days placement of Bromelain extract paste

Post evaluation of E.faecalis counts obtained after 7 days placement of Grape seed extract paste

to compare amongst them

研究设计

研究类型
Interventional
分配方式
Na
盲法
Participant Blinded

入排标准

年龄范围
14.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • single rooted maxillary and mandibular anteriors and mandibular premolars -teeth with caries and old restorations -teeth having diagnosed with necrotic and infected pulp clinically -radiographically periapical lesions with PAI Index score 1 to 3 -patients without any systemic diseases.

排除标准

  • patients with known medical history -pregnant women -cases requiring retreatment -teeth with calcified canals, immature apex, sinus opening, external and internal resorption and teeth exhibiting grade III mobility -periapical lesions with PAI index score 4 and 5.

结局指标

主要结局

Reduction in Enterococcus Feacalis count after placement of intracanal medicaments

时间窗: -preevaluation of E.feacalis count 72 hous after access and shaping | -post evaluation of E.feacalis count after 1 week with all three intracanal medicaments

次要结局

未报告次要终点

研究者

发起方
Siddhpur Dental College and Hospital
申办方类型
Other [Siddhpur Dental College]
责任方
Principal Investigator
主要研究者

Dr Nimisha Chaudhary

Siddhpur Dental College and Hospital

研究点 (1)

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