A novel genetic cause of congenital central hypothyroidism.

Completed

• Conditions: Central hypothyroidism; 10021112; low blood levels of thyroid hormone because thyroid gland is insufficiently activated

• Registration Number: NL-OMON43775
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- Congenital central hypothyroidism.
- First- or second-degree relative of a patient with congenital central hypothyroidism.

Exclusion Criteria

Carrier of other genetic defects known to cause congenital central hypothyroidism.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) The frequency of mutations of this gene in patients with central<br /><br>hypothyroidism and their first- and second-degree relatives</p><br>