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Clinical Trials/NCT03633136
NCT03633136
Completed
N/A

Improving Health Outcomes of Kidney Recipients: A Randomized Controlled Trial of a Pre-Transplant Education Intervention

University of Saskatchewan2 sites in 1 country162 target enrollmentJune 1, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Kidney Transplant
Sponsor
University of Saskatchewan
Enrollment
162
Locations
2
Primary Endpoint
Change in transplant knowledge score between the intervention and control groups as measured by the Kidney Transplant Understanding Tool (K-TUT)
Status
Completed
Last Updated
last year

Overview

Brief Summary

A multi-center, randomized, controlled clinical trial will be conducted to test the effectiveness of a home-based video intervention on improving kidney transplant candidate's knowledge, self-efficacy, quality of life, beliefs in medications, and education satisfaction as compared to usual care.

Detailed Description

Kidney transplantation is the best treatment for most patients with end-stage kidney disease, but it is an extremely complicated process. To become active on the transplant waitlist, patients must learn new information, navigate the healthcare system and undergo several specialized tests. After the transplant, another set of challenges emerge. Transplant recipients must commit to lifelong therapy with immunosuppressive medications and adapt to lifestyle changes. Up to half of all patients have difficulty taking the medications as prescribed, which can lead to transplant rejection, kidney loss, and death. The transplant process is challenging and confusing; however, increasing education and support to transplant candidates demands greater use of care providers' time and resources in a health care system that is already stretched. A patient-oriented video series has been developed according to best practices for transplant education, featuring an animated character embarking on a transplant journey. Animated segments illustrate difficult concepts for patients with poor health literacy, and patient narratives provide support and encouragement. A multi-center, randomized, controlled clinical trial will be conducted to test the effectiveness of a home-based video intervention on improving kidney transplant candidate's knowledge, self-efficacy, quality of life and beliefs in medications as compared to usual care. Participants will be randomized (1:1) to the control group, or the intervention group, who will be provided access to the video series, in addition, to standard of care. Differences in changes in transplant knowledge, self-efficacy, beliefs about medicines, quality of life, and education satisfaction will be evaluated by a pre-and post-intervention survey. A thorough assessment of video-viewing habits and satisfaction with the intervention will provide insight on the feasibility of expanding home-based education to other health settings.

Registry
clinicaltrials.gov
Start Date
June 1, 2018
End Date
July 7, 2020
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Holly Mansell

Associate Professor, College of Pharmacy and Nutrition

University of Saskatchewan

Eligibility Criteria

Inclusion Criteria

  • 18 or older
  • can speak and understand and read English
  • are being assessed or wait-listed for kidney transplantation

Exclusion Criteria

  • do not meet inclusion criteria

Outcomes

Primary Outcomes

Change in transplant knowledge score between the intervention and control groups as measured by the Kidney Transplant Understanding Tool (K-TUT)

Time Frame: 1 month

Measured by the Kidney Transplant Understanding Tool (K-TUT) (self-reported electronic survey). The K-TUT consists of 9 true/false and 13 multiple-choice questions, and scores are based on the number correct answers \[YES/ NO format\] of 69 items.

Secondary Outcomes

  • Difference in self-efficacy between the intervention and control group as measured by the Generalized Self Efficacy Scale (GSE)(1 month)
  • Difference in beliefs of medicine between the intervention and control group as measured by the Beliefs of Medicine Questionnaire (BMQ)(1 month)
  • Difference in quality of life between the intervention and control group as measured by the Short Form-12 (SF-12)(1 month)
  • Difference in education satisfaction between the intervention and control group as measured by self-reported electronic survey(1 month)

Study Sites (2)

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