Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study
Not Applicable
Completed
- Conditions
- Knee Osteoarthritis
- Interventions
- Dietary Supplement: Methylsulfonylmethane (MSM)
- Registration Number
- NCT01188213
- Lead Sponsor
- Assaf-Harofeh Medical Center
- Brief Summary
The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
- radiographic confirmed knee OA according to the Kellgren & Lawrence scale
Exclusion Criteria
- acute septic arthritis
- inflammatory arthritis
- any other type of arthritis
- history of knee buckling or recent knee injury
- lack of physical or mental bility to perform or comply with the treatment procedure
- diabetes mellitus
- fibromyalgia or other chronic pain syndromes
- concurrent anti-coagulant/anti-platelet drugs
- arthroscopy or intra-articular injections in the previous 3 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Purified MSM Methylsulfonylmethane (MSM) -
- Primary Outcome Measures
Name Time Method WOMAC questionnaire
- Secondary Outcome Measures
Name Time Method