The evaluations of the incident rate of and risk factors for development of cognitive dysfunction in each surgical types of cardiovascular surgery
Not Applicable
- Conditions
- Patients for cardiovascular surgery
- Registration Number
- JPRN-UMIN000030428
- Lead Sponsor
- Yamaguchi University
- Brief Summary
In 103 patients with aortic valve replacement, arteriosclerotic of ascending and descending aorta and carotid were risk factors for postoperative cognitive dysfunction (POCD).In 29 cases with aortic aneurysm surgery and 34 cases of other cardiac surgery, no association of blood concentration of ADMA, arginine, EPA and arachidonic acid with POCD were observed in these cases. In 91 cases of mitral valve surgery, mitral valve calcification was one of the risk factors for development of POCD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
Cases with neurological disease, symptomatic cerebral infarction,impossible for performing neuropsychological test, acute phase of infective endocarditis, emergency case and without the evaluation of chest CT and brain MRI.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method