Impact of Clinical Pharmacy Service on Patient Care and Cost Saving
试验速览
- 阶段
- 不适用
- 入组人数
- 576
- 主要终点
- The number of drug therapy problems
研究概览
简要总结
Background: Pharmacists have been proven to improve patient outcomes, medication adherence, glycemic control, reduce blood pressure, low-density lipoprotein, health care costs and length of hospital stay, and enhance quality of life.
Objective: to measure the impact of clinical pharmacy service on patient care and cost saving of patients at inpatient wards and ambulatory care clinics of Jimma University Specialized Hospital.
Methods: single center Randomized Controlled Trial will be conducted. Participants will be assigned to either pharmacy professionals' intervention group or non-intervention (control) group based on computer generated random number. The study will be done from July 26 to September 15, 2016. The total sample size is calculated with Open Epi online sample size calculator with 95% CI and 80% power. The total sample size is found to be 146 for inpatients and 473 for outpatients. Linear regression, student's t-test, logistic regression and chi-square test will be used for statistical analysis. Variables with p<0.05 will be considered statistically significant.
详细描述
Many studies have shown the positive impact of clinical pharmacy service on clinical, economic and humanistic outcomes. This type of service may be highly important in saving lives, improving patient outcomes, and decreasing treatment costs particularly in resource-limited settings like Ethiopia with a double burden of communicable and non-communicable diseases which need medication therapy. Though patients may experience a number of problems related to drug therapy, no study is conducted in Ethiopia to show the impact of clinical pharmacy service in alleviating such treatment related problems.
Therefore, this study aims to answer the following research questions.
impact of clinical pharmacy service in improving patient outcome and reducing cost of treatment of chronic illness patients
impact of clinical pharmacy service in improving patient outcome and reducing cost of treatment of hospitalized patients
Study site location and participants: this randomized controlled trial will be conducted at Jimma University Specialized Hospital, Southwest Ethiopia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years old,
- •Patients admitted to internal medicine ward,
- •Ambulatory patients with the following non-communicable diseases:
- •diabetes mellitus,
- •hypertension,
- •heart failure,
- •ischemic heart disease,
- •rheumatoid heart diseases,
- •chronic kidney disease,
- •venous thromboembolism,
- •asthma, chronic obstructive pulmonary disease, and epilepsy who have been on treatment for at least three months.
排除标准
- •Hospitalized medical inpatients with the following conditions.
- •Drop outs:
- •Patients leaving against medical advice, die and abscond within 72 hours of admission.
- •Patients not willing to participate.
- •Patients who may be transferred from intensive care unit to internal medicine ward.
- •Patients who may be transferred from other wards to internal medicine ward.
- •Patients admitted with stroke.
- •Chronic illness ambulatory patients with the following conditions:
- •Patients not willing to participate.
- •Women with gestational diabetes.
结局指标
主要结局
The number of drug therapy problems
时间窗: through study completion, an average of 8 weeks
The number of medication errors
时间窗: through study completion, an average of 8 weeks
Cost of medicines
时间窗: through study completion, an average of 8 weeks
次要结局
- Length of hospital stay(through study completion, an average of 8 weeks)
- In hospital mortality(through study completion, an average of 8 weeks)
研究者
Tigestu Alemu
Lecturer and clinical pharmacist
Jimma University