NCT00144053已完成3 期
A Phase Ⅲ Randomized Study of Mitomycin/Vindesine/Cisplatin Versus Irinotecan/Carboplatin Versus Paclitaxel/Carboplatin With Concurrent Thoracic Radiotherapy for Unresectable Stage Ⅲ Non-Small-Cell Lung Cancer
West Japan Thoracic Oncology Group0 个研究点目标入组 450 人开始时间: 2001年4月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 450
- 主要终点
- Survival
研究概览
简要总结
To evaluate whether two weekly concurrent chemoradiotherapy regimens offer any advantage over concurrent chemoradiotherapy regimens with Cisplatin, Vindesine, Mitomycin for unresectable stage III NSCLC.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients had histologically or cytologically confirmed locally advanced NSCLC. All patients must not have undergone any previous therapy for NSCLC. Patients had to have measurable disease, an Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1, and to be less than 75 years old. Adequate organ (bone marrow, renal, liver, heart, and lung) function was required. All patients gave written informed consent.
排除标准
- •The exclusion criteria consisted of pulmonary fibrosis, pleural effusion, pregnancy, lactation, active concurrent malignancies, severe drug allergies, myocardial infarction, severe heart disease, uncontrollable diabetes mellitus, and infection. -
结局指标
主要结局
Survival
次要结局
- safety
研究者
相似试验
Unknown
2 期
Concurrent Radiotherapy and Weekly Chemotherapy of PF for Postoperative Locoregional Recurrence of Esophageal CancerEsophageal Squamous Cell CarcinomaNCT02325986Sun Yat-sen University46
已完成
3 期
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed RhabdomyosarcomaRhabdomyosarcomaAdult RhabdomyosarcomaChildhood Botryoid-Type Embryonal RhabdomyosarcomaStage I Adult Soft Tissue Sarcoma AJCC v7Stage III Adult Soft Tissue Sarcoma AJCC v7Localized Childhood Soft Tissue SarcomaChildhood Alveolar RhabdomyosarcomaChildhood Embryonal RhabdomyosarcomaStage II Adult Soft Tissue Sarcoma AJCC v7SarcomaNCT00354835Children's Oncology Group481
已完成
3 期
Combination Chemotherapy in Treating Patients With Previously Untreated RhabdomyosarcomaAdult Malignant MesenchymomaAdult RhabdomyosarcomaAlveolar Childhood RhabdomyosarcomaChildhood Malignant MesenchymomaEmbryonal Childhood RhabdomyosarcomaEmbryonal-botryoid Childhood RhabdomyosarcomaNonmetastatic Childhood Soft Tissue SarcomaPreviously Untreated Childhood RhabdomyosarcomaStage I Adult Soft Tissue SarcomaStage II Adult Soft Tissue SarcomaStage III Adult Soft Tissue SarcomaNCT00003958Children's Oncology Group702
终止
3 期
Randomised Study of Concomitant Radiochemotherapy in Non-small Cell Lung CancerNon-small Cell Lung CarcinomaNCT00633568European Lung Cancer Working Party125
进行中（未招募）
3 期
Phase Ⅲ Trial of Adjuvant Chemotherapy in Patients With N2-3 Nasopharyngeal CarcinomaNasopharyngeal CarcinomaNCT03321539Sun Yat-sen University216