Desmopressin for the Treatment of Orthostatic Hypotension and Excessive Nighttime Urination in Parkinson’s Disease

Phase 2

Recruiting

• Conditions: Neurological - Parkinson's disease; octuria; Parkinson's Disease; Orthostatic Hypotension; Nocturia; Neurological - Other neurological disorders; Renal and Urogenital - Other renal and urogenital disorders

• Registration Number: ACTRN12609000080224
• Lead Sponsor: John O'Sullivan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-02-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Parkinson's disease
Orthostatic hypotension (blood pressure drop with standing)
A need to empty the bladder 2 or more times at night

Exclusion Criteria

History of renal failure, congestive heart failure, or cirrhosis
A history of low blood sodium
Dementia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of at least 2 points on the COMPASS-OD survey, which assesses for symptoms of low blood pressure.[Assessed at day 21 and 49];Number of nocturnal bladder voids as measured by a diary[Assessed at day 21 and 49]

Secondary Outcome Measures

Name	Time	Method
Improvement in sleep as measured by a survey (Epworth Sleepiness Scale)[Assessed at day 21 and 49]