Treatment considerations for the surgical therapy of peri-implantitis - Surgical considerations in treating peri-implantitis

niversitair Medisch Centrum Groningen0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月8日

适应症

试验速览

暂无简介。

•- the patient is >=18 years of age;
•- adult patients with at least one endosseous implant in the oral cavity with
•clinical and radiographical evidence of peri-implantitis. Peri-implantitis is
•defined as probing pocket depth (PPD) of >= 6mm in combination with bleeding on
•probing (BOP) or suppuration on probing (SOP) and radiographic bone loss of
•>=3mm after placing the definitive suprastructure;
•- the implants have been in function for at least 2 years;
•- the patient is capable of understanding and giving informed consent.

•Exclusion criteria prior to pre-treatment:
•- medical and general contra-indications for the procedure;
•- a history of local radiotherapy to the head and neck region;
•- pregnancy and lactation;
•- uncontrolled diabetes mellitus (HbA1c <7% or <53 mmol/mol);
•- use of intravenous bisphosphonates;
•- known allergy to chlorhexidine, amoxicillin and/or metronidazole;
•- significant contra-indications to the use of antibiotics due to other
•- long-term use of anti-inflammatory drugs
•- patient is incapable of performing basic oral hygiene measures as a result of
•physical or mental disorders;
•- implants with bone loss exceeding 2/3 of implant length or implants with bone
•loss beyond the transverse openings in hollow implants;
•- previous surgical treatment of the peri-implantitis lesions;
•- chronic bronchitis or asthma.
•Additional exclusion criteria after pre-treatment:
•- no peri-implantitis remaining: minor bleeding on probing (< 20%), probing
•pocket depth < 6mm, plaque < 20%;
•- active periodontal disease at the remaining dentition (probing pocket depth >=
•6mm, bleeding on probing >= 20%) or insufficient oral hygiene (plaque >= 20%);
•- use of antibiotics during the last 3 months.

发起方