Respiratory Proprioceptive Neuromuscular Facilitation Technique in Chronic Pulmonary Obstructive Disease Patients.

Not Applicable

Completed

• Conditions: COPD
• Interventions: Other: Conventional; Other: PNF

• Registration Number: NCT05876403
• Lead Sponsor: Riphah International University

Brief Summary

The purpose of this study is to evaluate the impact of PNF technique combined with aerobic exercises among COPD patients in a clinical setting. Previous literature has evaluated this technique in ventilated patients but in clinical setting specifically in Pakistan, this invention therapy has not been implied in COPD patients.

Detailed Description

Chronic Obstructive Pulmonary Disorder manifested as breathlessness, respiratory difficulties and persistent cough is one of the biggest causes of mortality around the world. 2.1% of Pakistani population has COPD. Proprioceptive neuromuscular facilitation is used as management technique in which muscle stretching promotes chest wall mobility and restores regular breathing rhythm. In previous studies, PNF technique combined with aerobic exercises has been utilized to improve Pulmonary functions in COPD patients. But the sample size of these studies was small and participants were ventilated patients, hence not targeting the diaphragm. Our study shall evaluate the impact of PNF technique combined with aerobic training on the Pulmonary function of COPD patients in the clinical setting.

Study Timeline

• Study First Submitted: 2023-05-17
• Study First Submitted QC: 2023-05-24
• Study First Posted: 2023-05-25
• Study Start: 2023-09-01
• Primary Completion: 2023-11-15
• Study Completion: 2023-12-15
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-28
• Last Update Posted: 2024-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Both male & female participants.
• Diagnosed COPD patients
• Age 35-60years
• Ratio of forced expiratory volume in first second & forced vital capacity(FEV1/FVC <0.7,30%<FEV1<80%
• Stable clinical condition.

Exclusion Criteria

• Serious conditions with require supplementary oxygen or ventilator/support devices.
• COPD exacerbation within last 4weeks
• Patients with recent chest wall trauma, surgery or deformity.
• Patient with neurological, psychological, musculoskeletal, or cardiac medical history.
• Pulmonary disease with physical impairment.
• Inability to follow the pulmonary rehabilitation program.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional	Conventional	The protocol for controlled group will consist of 35-60years old participants with moderate to severe COPD. At baseline measurements will be collected and COPD assessment test (CAT) and Modified Borg Scale will be taken. Participants will then be made to perform breathing and aerobic exercises (3sessions per week) for 6 weeks and after every 2 weeks outcome measures will be evaluated using chest expansion, spirometry, and 6 minutes walk test (6MWT) along with CAT and Modified Borg Scale.
PNF Techniques	PNF	The same protocol will be followed for the 30 participants of experimental group where after the baseline measurements, participants will perform breathing and aerobic exercises along with PNF techniques (3 sessions per week for 6 weeks). The outcome Measures will be measured after every 2 weeks through Spirometry, CAT, Modified Borg Dyspnea Scale and 6 minutes walk test

Primary Outcome Measures

Name	Time	Method
Forced expiratory volume in 1sec (FEV1)	two weeks	Forced expiratory volume in 1sec (FEV1) measured through digital spirometer. If the value of FEV1 is within 80% of the reference value, the results are considered normal
Chest Expansion	two weeks	The expansion of chest during breathing will be measures and axillary, nipple and xiphisternal level using a measuring tape.
Modified Borg Dyspnea Scale	two weeks	Participants will fill this 12 points Scale to show breathing difficulty from 0 to 10.
COPD assessment test	two weeks	8 points questionnaire will evaluate patients Pulmonary function capacity through semantic 6 point difference Scale.
Peak expiratory flow rate (PEFR)	two weeks	Peak expiratory flow rate (PEFR) Peak expiratory flow rate (PEFR) measured through digital spirometer. Peak Expiratory Flow Rate (PEFR) measured through digital spirometer. Three zones of measurement are commonly used to interpret peak flow rates. Normal value of PEFR is (80-100%). Green zone indicates 80 to 100 percent of the usual or normal peak flow reading, yellow zone indicates 50 to 79 percent of the usual or normal peak flow readings, and red zone indicates less than 50 percent of the usual or normal peak flow readings.
Forced vital capacity (FVC)	two weeks	Forced vital capacity (FVC) measured through digital spirometer. If the value of FVC is within 80% of the reference value, the results are considered normal.; Changes in FVC from baseline to 5th and after 15th day of intervention will be assessed.

Secondary Outcome Measures

Name	Time	Method
6 minutes walk test:	two weeks	This test with minimum important distance of 25 metres will assess aerobic \& functional capacity of participants in a 6 minutes walk.

Trial Locations

Locations (1)

Pakistan Railway General Hospital; 🇵🇰 Islamabad, AL, Pakistan