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Effects of combined therapy of upper body elebation and highflow nasal cannula on postoperative high-sensitivity troponin T in severe obstructive sleep apnea patients undergoing major surgery: a randomized control study

Not Applicable
Recruiting
Conditions
myocardial injury after noncardiac surgery
Registration Number
JPRN-UMIN000048103
Lead Sponsor
Chiba University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

1. emergency surgery 2. palliative operation 3. severe renal dysfunction (eGFR<15 or dialysis patients) 4. severe respiratory disease with hypoxemia and/or hypercapnia 5. oxygen therapy before surgery 6. unable to accept high-flow nasal cannula therapy 7. renal and ureteral surgery 8. sepsis 9. use of antimicrobials before surgery 10. pulmonary embolism 11. preoperative high-sensitivity troponin T levels greater than or equal to0.065 ng/mL 12. difficulty of obtaining concents from the patient 13. judged by the principal investigator to be inappropriate as a participant

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
maximum difference of high-sensitivity troponin T before and after surgery
Secondary Outcome Measures
NameTimeMethod
incidence of Myocardial Injury after Non-cardiac Surgery, incidence of high-sensitivity troponin T greater than 0.005 ng/mL, major postoperative complications within 30 days after surgery,
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