A clinical trial to study the effect of Oral Laser Light vs. Medication in Treating oral lichen planus which is a disease that causes burning sensation in mouth.

Phase 2

Not yet recruiting

• Conditions: Other and unspecified lesions of oral mucosa,

• Registration Number: CTRI/2024/02/063136
• Lead Sponsor: Dr Aparna Raj

Brief Summary

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|This study is the Two arm concurrent parallel experimental study Comparing of the efficacy of Photodynamic Therapy(Methylene blue using soft tissue diode LASER)with Topical Tacrolimus in the management of patients with Oral Lichen Planus.

It is the study for post-graduation Main dissertation/thesis and will be done in the institution in the Department of Oral Medicine and Radiology of PCDS, Bhopal,M.P.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-03
• Last Update Posted: 2024-02-22

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

clinically and histopathologically cofirmed cases of lichen planus, patients who have cleared the patch test for tacrollimus participants wiiling to be part of the study and have signed informed consent.

Exclusion Criteria

• patients having other autoimmune disorders.
• patients who are already under going gtreatment for lichen planus.
• pregnant and lactating women.
• patient with allergies to methyllene blue,tacrollimus,LASERS.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Independent variables- Tacrolimus, Photodynamic therapy	8 weeks
Dependent variables-burning sensation,pain,size of lesion	8 weeks

Secondary Outcome Measures

Name	Time	Method
Dependent variables - Dependent variable-Burning sensation, pain, size of the lesion	Independent variables- Tacrolimus, Photodynamic therapy

Trial Locations

Locations (1)

1. PEOPLES COLLEGE OF DENTAL SCIENCES AND RESEARCH CENTRE; 🇮🇳 Bhopal, MADHYA PRADESH, India

1. PEOPLES COLLEGE OF DENTAL SCIENCES AND RESEARCH CENTRE

🇮🇳Bhopal, MADHYA PRADESH, India

Dr Aparna Raj

Principal investigator

9650249975

aparnarajsingh1513@gmail.com