Non-phonatory Exercises in Patients with Unilateral Vocal Fold Paralysis Post-thyroidectomy
- Conditions
- Unilateral Vocal Cord Paralysis
- Interventions
- Behavioral: Non-phonatory exercises
- Registration Number
- NCT05963165
- Brief Summary
Thyroidectomy is the most common iatrogenic cause of vocal fold paralysis. Patients complain of hoarseness caused by incomplete glottic closure and have effort to raise vocal intensity with consequent elevation of the larynx and/or involvement of supraglottic structures in phonation. These compensation mechanisms result in a shift of the fundamental frequency towards more serious tones or falsetto voice emissions.
The first choice treatment is speech therapy which aims to obtain better glottic closure, preventing ankylosis of the crico-arytenoid joint. In order to promote better glottic closure without risking the onset or increase of dysfunctional compensation, the idea behind this project is to propose non-phonatory adduction exercises in the first post-operative week.
The primary objective of the study is to compare patients who will perform non-phonatory exercises in parallel with medical therapy for one week and patients who will perform standard medical therapy only during the first week.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56
- vocal fold paralysis after thyrodectomy
- ability to sign an informed consent
- Vocal fold paralysis with different etiology
- Previous history of laryngeal, pulmonary or gastric surgery
- History of vocal or laryngeal pathologies that have required therapy
- Current or previous lung disorders
- Hearing loss
- Motor or neurological deficits
- Presence of malignant diseases
- Presence of speech or reading disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Experimental group Non-phonatory exercises Patients who will perform non-phonatory exercises in parallel with medical therapy for the first week
- Primary Outcome Measures
Name Time Method Degree of glottic closure 3 months A videostrobolaryngoscopy will be performed. The recorded videos will be viewed by expert clinicians and a numerical score will be assigned relating to the degree of glottic adduction on a 7-point scale.
- Secondary Outcome Measures
Name Time Method Acoustic analysis (fundamental frequency) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the Fundamental Frequency (F0, Hz) will be analysed.
Acoustic analysis (NHR) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the noise/harmonics ratio (NHR) will be analysed.
Acoustic analysis (Shimmer%) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the Shimmer ( %) will be analysed.
fAcoustic analysis (Jitter%) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the Jitter (%) will be analysed.
Acoustic analysis (intensity) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the intensity (dB) will be analysed.
Acoustic analysis (Flow) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the minimum frequency (Flow) will be analysed.
Acoustic analysis (Fhigh) 3 months Through the use of the "Praat" software, on the reading of the piece "The desert" and on a sustained /a/ the maximum frequency (Fhigh) will be analysed.
MPT 3 months the Maximum Phonatory Time (MPT) will be evaluated on a sustained /a/ (minimum 3 seconds)
Trial Locations
- Locations (1)
Fondazione Policlinico Universitario A. Gemelli - IRCCS
🇮🇹Roma, Italy