NCT01456923CompletedPhase 1
Phase 1 Study Of The Efficacy Of Chemotherapy With DNA Damaging Agents Versus Surgery In Colorectal Cancer
Centro Hospitalar Nordeste0 sitesStarted: October 21, 2011Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
Study Overview
Brief Summary
Chemotherapy Treatment alone with DNA damaging drugs might be as effective as chemotherapy combined with surgery in colorectal cancer (CRC) avoiding surgery complications.
Study Design
- Study Type
- Interventional
- Primary Purpose
- Treatment
Eligibility Criteria
- Ages
- 40 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •- patients that did not underwent surgery
Exclusion Criteria
- •- patients that underwent surgery
Arms & Interventions
Control (chemotherapy and surgery)
Active Comparator
Patients treated with chemotherapy + surgery
Intervention: surgery (Procedure)
Control (chemotherapy and surgery)
Active Comparator
Patients treated with chemotherapy + surgery
Intervention: Treatment with chemotherapy (Other)
Study
Active Comparator
Patients treated only with chemotherapy
Intervention: Only chemotherapy treatment for study cohort (Other)
Investigators
Ana Cadavez Pedro
Principal Investigator
Centro Hospitalar Nordeste
Similar Trials
Completed
Phase 1
feasibility and efficacy of chemotherapy combined with zoledronic acid : phase I/II trial for adult T-cell leukemia/lymphoma (ZAAT study)JPRN-UMIN000007569Saga University, Faculty of Medicine, Devision of Hematology and Oncology21
Completed
Phase 2
Carboplatin Plus Vincristine in Treating Children With RetinoblastomaRetinoblastomaNCT00002794St. Jude Children's Research Hospital25
Completed
Phase 1
Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal CancerExtrahepatic Bile Duct CancerGallbladder CancerGastrointestinal Carcinoid TumorSmall Intestine CancerColorectal CancerPancreatic CancerGastric CancerEsophageal CancerLiver CancerAnal CancerNCT00003427Memorial Sloan Kettering Cancer Center36
Unknown
Phase 1
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced and/or Recurrent Head and Neck CancerHead and Neck CancerNCT00004097National Cancer Institute (NCI)
Completed
Phase 1
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth CancerHead and Neck CancerNCT00004901Robert H. Lurie Cancer Center