Validation of Low Anterior Resection Syndrome Score in Korean Version
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 主要终点
- Quality of life in association to the severity of bowel dysfunction
研究概览
简要总结
In contemporary era of rectal cancer treatment, development of surgical technique and tool, adaptation of chemoradiation therapy, as well as multidisciplinary approach have led increased survival as well as rate of sphincter preservation. However, poor anorectal function, such as fecal incontinence and/or urgency, has also been increased. Such anorectal dysfunction is named as low anterior resection syndrome, and its rate has been reported in 40 to 90% in rectal cancer patients who received sphincter preserving surgery. Low anterior resection syndrome is known to debilitate quality of life in survivors of rectal cancer. Previously, several studies attempted to evaluate the low anterior resection syndrome via questionnaires and scoring system. Adapting the low anterior resection syndrome score system created in Denmark, this study investigates the validity of the scoring system in Korean language.
详细描述
In this study, the low anterior resection syndrome score questionnaire proposed by Therese Juul is translated to Korean language by 3 different professional translators. Patients who received sphincter saving surgery to treat rectal cancer will be asked to fill up the questionnaire. Compiling the results, the quality of life after sphincter preserving surgery will be investigated in the association with the low anterior resection syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 20-80
- •surgery undertook from Jan. 2009 to Dec. 2016
- •diagnosed with adenocarcinoma
- •curative intent of surgery
- •planned surgery
- •sphincter saving surgery
排除标准
- •patients with stage IV
- •emergency surgery
- •patients with recurrent disease
结局指标
主要结局
Quality of life in association to the severity of bowel dysfunction
时间窗: 3 months follow-up, 6 months follow-up, 1 year follow-up, 2 year follow-up, 3 year follow-up, 4 year follow-up, 5 year follow-up, beyond 5 year follow-up
The change in the quality of life will be evaluated based on the questionnaire in regard to bowel dysfunction
次要结局
未报告次要终点
研究者
Hyung Jin Kim
Assistant Professor
Saint Vincent's Hospital, Korea
