Pathophysiology and visual prognosis of cases with submacular hemorrhage: multicenter retrospective observational study
Not Applicable
- Conditions
- Submacular hemorrhage associated with wet age related macular degeneration, retinal macroaneurysm or any other disease.
- Registration Number
- JPRN-UMIN000036698
- Lead Sponsor
- Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences.
- Brief Summary
Sixty-seven percent of the patients were treatment naive. Thirty-six eyes (28%) had undergone vitrectomy, 49 eyes (39%) had undergone gas pneumatic displacement, and 42 eyes (33%) had undergone anti-VEGF monotherapy. With pneumatic displacement and vitrectomy, SRH decreased to within 1 papillary diameter in more than 40% of postoperative cases. Final mean visual acuity (decimal unit) significantly improved from 0.13 to 0.23 and from 0.07 to 0.18, respectively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 127
Inclusion Criteria
Not provided
Exclusion Criteria
Cases in which the affected eye has a complication of retinal detachment, diabetes retinopathy, retinal vein occlusion, uveitis and other retinal vitreous diseases. Cases that do not agree to provide data.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Best corrected visual acuity (BCVA) and change of BCVA
- Secondary Outcome Measures
Name Time Method Findings as fundus and optical coherence tomography at and after hemorrhage Pathology and treatment history before bleeding in age related macular degeneration Kind of treatment and its effect Association with systemic complications and oral administration