MedPath

Brexpiprazole in patients with schizophrenia

Phase 1
Conditions
Schizophrenia
MedDRA version: 14.1Level: PTClassification code 10039626Term: SchizophreniaSystem Organ Class: 10037175 - Psychiatric disorders
Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]
Registration Number
EUCTR2012-002705-21-CZ
Lead Sponsor
H. Lundbeck A/S
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
210
Inclusion Criteria

• The patient has completed the lead-in study 14644A.
• The patient is judged to potentially benefit from 52-week treatment with
brexpiprazole according to the clinical opinion of the investigator.
• The patient agrees to protocol-defined use of effective contraception.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 137
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 3

Exclusion Criteria

• The patient has been diagnosed with a primary psychiatric disorder other
than schizophrenia during Study 14644A.
• The patient has a clinically significant unstable illness diagnosed during
Study 14644A.
• The patient, in the opinion of the investigator or according to Columbia-
Suicide Severity Rating Scale (C-SSRS), is at significant risk of suicide.
• The patient has an abnormal ECG or other abnormal ECG tests that are, in
the investigator's opinion, clinically significant.
• The patient is, in the investigator's opinion, unlikely to comply with the
protocol or is unsuitable for any reason.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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