Effect of two different doses of Tacrolimus eye ointment in Chronic allergic Conjunctivitis
Phase 3
- Conditions
- Health Condition 1: H104- Chronic conjunctivitis
- Registration Number
- CTRI/2023/09/057951
- Lead Sponsor
- KAHER JGMM Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age >14yrs
2.Active bilateral severe VKC responding poorly despite >1 month of treatment with topical anti allergic agents and corticosteroids.
Exclusion Criteria
1.Patients with adnexal abnormalities, glaucoma, contact lens wearer, corneal pathology will be excluded from the study.
2.Patients who have received immunosuppressive therapy
3.Patients with known hypersensitivity to Tacrolimus eye ointment
4.Pregnant and lactating women will be excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in mean scores of ocular symptoms and signs at 2nd week, 4th week, 6th week and 8th week from baseline. <br/ ><br>Timepoint: <br/ ><br>All the parameters will be evaluated at baseline visit, day 14, day 30 & day 45.
- Secondary Outcome Measures
Name Time Method Secondary outcome measures: <br/ ><br>1.Subjective scoring of symptoms at baseline, 2nd week, 4th week, 6th week & 8th week. <br/ ><br>2.Any adverse effects from the treatment reported. <br/ ><br>Timepoint: All the parameters will be evaluated at baseline visit, day 14, day 30 & day 45.